Chronic Renal Complications and Their Risks in Thalassemic Patients Receiving Transfusion

Our study aimed to describe the prevalence, main clinical features, and risk factors for renal and urinary tract complications in patients with thalassemia. This study assessed renal complications and their main clinical features in 177 thalassemic patients evaluated between 2025 and 2026 and compared the results with renal complications observed in sickle cell anemia. This study evaluated 177 patients with thalassemia examined between 2025 and 2026. Findings from renal ultrasonography alongside clinical data regarding age contribution, transfusion therapy, and detected renal pathologies were analyzed. Additionally, the clinical utility of clinical parameters and ultrasound findings in assessing renal function was reviewed. Finally, this study investigated the primary mechanisms of renal damage in thalassemia, highlighting key differences from the renal changes characteristic of sickle cell anemia.