Cancer Genetics: Comprehensive Analysis of Genetic Variants and Molecular Biomarkers Associated with Cancer Progression and Patient Survival

The development and expansion of cancer are mainly due to heterogeneous genetic structures caused by somatic mutations and several epigenetic changes. here, the expansion and development of the tumor cell and at the same time how long the metastatic artis and cancer patients can survive and at the same time the molecular markers that determine this are seriously evaluated. In addition, the transformation of malignant cells and the basic changes that occur in oncogenes and cells, as well as indels and point mutations, are discussed in a broad way. One of the researched areas is the effect of polymorphism on cancer cells and their treatment, its instability, mutational burden, and transcriptomic expressions; and the use of biomarkers for various purposes, such as prognostic and predictive purposes, is mainly investigated. In addition, many studies- nextgeneration sequencing, finding biomarkers of genome association studies, and new changes in the identification of genes up to the molecular level are also included. In order to improve the treatment results of cancer patients and to optimize the treatment, the correlation of multi-omic data with medical information is widely used.